By Lizzy Smith | Posted - Apr 4th, 2015





Bendamustine, Thalidomide and Dex: Viable Salvage Option for Double-Relapsed/Refractory Myeloma Patients

Bendamustine plus thalidomide and dexamethasone may be a viable salvage option for the treatment of patients with double-relapsed/refractory multiple myeloma, a recent study published in the journal Annals of Hematology has shown. For the study, researchers retrospectively analyzed data from 30 patients with double-relapsed/refractory multiple myeloma who received bendamustine, thalidomide, and dexamethasone in 28-day cycles. Patients received a median of five cycles. Results showed that 87% of patients achieved stable disease or better. Median progression-free survival and overall survival were 4.0 and 7.2 months, respectively, at a median follow-up of 12.1 months. In regard to safety, the most common grade 3-4 adverse events were neutropenia, thrombocytopenia, and anemia. Other common treatment-associated side effects were infection, pain, and sensory neuropathy. For more details, click here.

Lizzy Smith
About the Author

Lizzy Smith - Lizzy Smith was diagnosed with myeloma in 2012 at age 44. Within days, she left her job, ended her marriage, moved, and entered treatment. "To the extent I'm able, I want to prove that despite life's biggest challenges, it is possible to survive and come out stronger than ever," she says.


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