By Jennifer Ahlstrom | Posted - Feb 11th, 2019





Gilead Drops Kite Multiple Myeloma CAR T Development

Gilead released fourth quarter results that removed an anti-BCMA cell therapy for multiple myeloma from it's pipeline, part of its $12 billion acquisition of Kite Pharma.

The decision to drop the KITE-585-CAR T programs indicates the ever growing competition in the BCMA-targeted therapy for myeloma and represents a loss of $820M in investment. 

Other anti-BCMA CAR T treatments are in development. At the recent ASH conference in San Diego, there were more than 10 different anti-BCMA regiments including CAR T therapies, bi-specific antibodies and antibody-drug conjugates. These approaches come from Celgene, Novartis, Janssen, Amgen, GSK and others.  In addition, some major myeloma academic centers are also testing the manufacturing of their own CAR T therapy in-house, making the field even more crowded. 

Not all CAR T therapies are the same and at this time, it is uncertain which CAR T will provide the best deepest and longest benefit to patients. 

Jennifer Ahlstrom
About the Author

Jennifer Ahlstrom - Jenny A - Myeloma survivor, patient advocate, wife, mom of 6. Believer that patients can help accelerate a cure by weighing in and participating in clinical research. Founder of Myeloma Crowd by HealthTree and the HealthTree Foundation.


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