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FDA Removes Clinical Trial Hold on Cellectis Off-the-Shelf CAR T for Multiple Myeloma

CLINICAL TRIALS - November 18, 2020

The clinical trial hold for UCART, an allogeneic (off-the-shelf) CAR T product by Cellectis has been removed by the FDA and the MELANI-01 trial is now able to m... Read More

Belantamab Mafodotin Teams with SpringWorks Drug to Increase BCMA Expression in Early Myeloma Trial

CLINICAL TRIALS - August 04, 2020

An early Phase I clinical trial is combining GlaxoSmithKline's belentabmab mafodotin with SpringWorks Therapeutics' nirogacestat with people with re... Read More

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Myeloma Clinical Trials Explained: CLR-131

CLINICAL TRIALS - June 08, 2020

Written by Melissa McMahon, SparkCures At SparkCures, our mission is to help people with multiple myeloma find, understand and connect with their clinical tr... Read More

Feelings, Fatigue and Fitness: Help Roswell Park Myeloma Researcher Complete His Fitness/Health Myeloma Study

CLINICAL TRIALS - June 01, 2020

How do you feel right now? And how fit are you? Myeloma specialist Jens Hillengass, MD, Chief of the Roswell Park Cancer Institute multiple myeloma program is r... Read More

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XPOVIO (selinexor) Study Shows Impact When Used in Earlier Lines of Multiple Myeloma Therapy with Velcade and Dex

CLINICAL TRIALS - March 11, 2020

Using XPOVIO (selinexor) and Velcade weekly with low-dose dexamethasone showed a 47% increase in progression free survival compared to Velcade (twice weekly) ... Read More

Clinical Trial: Smoldering Myeloma Personalized Vaccine at MD Anderson

CLINICAL TRIALS - February 06, 2020

Could a vaccine prevent smoldering myeloma from progressing to active myeloma? An early Phase I clinical trial at MD Anderson Cancer Center is developing a pers... Read More

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Clinical Trial: Avelumab in Combination With Hypofractionated Radiotherapy in Patients With Relapsed Refractory Multiple Myeloma

CLINICAL TRIALS - June 28, 2019

This open-label, Phase 2 study is studying whether the monoclonal antibody Avelumab, in combination with radiation therapy, is safe in the treatment of relaps... Read More

Clinical Trial: Reducing Insomnia of Cancer Survivors with Yoga vs. Health Education and Cognitive Behavioral Therapy

CLINICAL TRIALS - March 28, 2019

How can myeloma patients sleep better when living with cancer? A new phase III study is comparing three groups: yoga, survivorship health education and cognit... Read More

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Clinical Trial: The MyDrug MMRF Study Recruiting for 228 Myeloma Patients

CLINICAL TRIALS - December 11, 2018

The MMRF announced the launch of a new clinical trial called MyDrug (Myeloma - Developing Regimens Using Genomics). The goal of the study ... Read More

Real World Vs. Clinical Trial Multiple Myeloma Outcomes Can Differ

CLINICAL TRIALS - August 22, 2018

Survival outcomes in real-world practice may not mirror outcomes found in clinical trials for non-transplant patients with multiple myeloma, according to rese... Read More

Clinical Trial: Daratumumab, Cytoxan, Dex and Velcade for Newly Diagnosed and Relapsed Myeloma

CLINICAL TRIALS - January 07, 2017

Daratumumab is now being used in many clinical trials in many different combinations. Because of its success in past clinical trials, it is moving to earlier us... Read More

An Update on INSIGHT Global Study (for Myeloma Treatment Effectiveness and Outcomes)

CLINICAL TRIALS - December 21, 2016

BY JIM OMEL In July, 2016 I explained INSIGHT, a truly global study of treatment and outcome data for myeloma patients gathered from around the world. The go... Read More

Clinical Trial: Adding Daratumumab to the Frontline for Newly Diagnosed Myeloma Patients

CLINICAL TRIALS - December 17, 2016

A new study is open at the Levine Cancer Institute (with many more sites to follow) adding daratumumab to Revlimid, Velcade and dexamethasone for newly diagnose... Read More


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