/
/
New HDAC Inhibitor for Multiple Myeloma In Early Chinese Study
New HDAC Inhibitor for Multiple Myeloma In Early Chinese Study image
New HDAC Inhibitor for Multiple Myeloma In Early Chinese Study
Posted Mar 14, 2019

A new HDAC inhibitor called CS3003 is now in a Phase I study in China for multiple myeloma patients. It is considered to be a HDAC6 inhibitor which is different from the pan-HDAC inhibitors approved in the US for myeloma like panobinostat. 

Dr. Jon Wang, Chief Scientific Officer of CStone said: 

"The selective inhibition of HDAC6 has the potential to produce better efficacy in multiple myeloma either as monotherapy or in combination with current standard of cares. Furthermore, preclinical data and early clinical studies of similar products in the same class have indicated that CS3003 has better safety profile than pan-HDAC inhibitors and the potential to develop combination therapies with immune checkpoint inhibitors for the treatment multiple types of solid tumors." 

This HDAC inhibitor has shown better impact and improved safety results over pan-HDAC inhibitors. It could also be combined with PD-L1 antibodies to expand the power of checkpoint inhibitors. 

The work is early and it will be interesting to see how it progresses through clinical studies. 

 

The author Jennifer Ahlstrom

about the author
Jennifer Ahlstrom

Myeloma survivor, patient advocate, wife, mom of 6. Believer that patients can help accelerate a cure by weighing in and participating in clinical research. Founder of Myeloma Crowd by HealthTree and the HealthTree Foundation.

More Myeloma News Articles

Get the latest thought leadership on Myeloma delivered straight to your inbox.

Subscribe to the weekly "HealthTree Community for Myeloma Newsletter" for Myeloma news, life with Myeloma stories, Myeloma clinical trials, Myeloma 101 articles and events with Myeloma experts.

Thanks to our HealthTree Community for Myeloma Sponsors:

Genentech
Abbvie
Bristol Myers Squibb
Janssen Oncology
GSK

Follow Us

facebook instagram twitter youtube

Copyright © 2022 HealthTree Foundation. All Rights Reserved.

The HealthTree Foundation / Myeloma Crowd is a qualified 501(c)(3) tax-exempt organization. Tax ID 45-5354811

 https://www.guidestar.org/profile/45-5354811