In November of 2018, the FDA approved a new combination for the use of elotuzumab - this time in combination with pomalidomide and dexamethasone. The approval was granted based on the results from the ELOQUENT-3 study showing that elo, pom and dex had better outcomes than pom and dex alone. Elotuzumab is typically never used by itself but provides benefit when used with an immonomodulator. So when patients relapse after taking Revlimid, now Pomalyst can be used instead. In the study, the researchers concluded:
Among patients with multiple myeloma in whom treatment with lenalidomide and a proteasome inhibitor had failed, the risk of progression or death was significantly lower among those who received elotuzumab plus pomalidomide and dexamethasone than among those who received pomalidomide plus dexamethasone alone.
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about the author
Myeloma survivor, patient advocate, wife, mom of 6. Believer that patients can help accelerate a cure by weighing in and participating in clinical research. Founder of Myeloma Crowd by HealthTree and the HealthTree Foundation.